Luca Antiga

Publications

Journal papers

• Paszke A, Gross S, Massa F, Lerer A, Bradbury J, Chanan G, Killeen T, Lin Z, Gimelshein N, Antiga L, Desmaison A, Kopf A, Yang E, DeVito Z, Raison M, Tejani A, Chilamkurthy S, Steiner B, Fang L, Bai J, Chintala S. PyTorch: An Imperative Style, High-Performance Deep Learning Library NeurIPS 2019.
• Vuillaume T, Jacquemont M, Antiga L, Benoit A, Lambert P, Maurin G, Silvestri G, and the CTA Consortium GammaLearn - first steps to apply Deep Learning to the Cherenkov Telescope Array data EPJ Web of Conferences 214, 06020 (2019).
• Jacquemont M, Antiga L, Vuillaume T, Silvestri G, Benoit A, Lambert P, Maurin G. Indexed Operations for Non-rectangular Lattices Applied to Convolutional Neural Networks VISAPP19.
• Silvestri G, Antiga L. Stereology as Weak Supervision for Medical Image Segmentation MIDL 2018.
• Kirienko M, Sollini M, Silvestri G, Mognetti S, Voulaz E, Antunovic L, Rossi A, Antiga L, Chiti A. Convolutional Neural Networks Promising in Lung Cancer T-Parameter Assessment on Baseline FDG-PET/CT. Contrast Media Mol Imaging 2018.
• Paszke A, Gross S, Chintala S, Chanan G, Yang E, DeVito Z, Lin Z, Desmaison A, Antiga L, Lerer A. Automatic differentiation in PyTorch. NIPS 2017.
• Ruggenenti P, Gentile G, Perico N, Perna A, Barcella L, Trillini M, Cortinovis M, Ferrer Siles CP, Reyes Loaeza JA, Aparicio MC, Fasolini G, Gaspari F, Martinetti D, Carrara F, Rubis N, Prandini S, Caroli A, Sharma K, Antiga L, Remuzzi A, Remuzzi G, and on behalf of the SIRENA 2 Study Group. Effect of Sirolimus on Disease Progression in Patients with Autosomal Dominant Polycystic Kidney Disease and CKD Stages 3b-4 CJASN, Epub ahead of print Feb 2016.
• Xiang J, Antiga L, Varble N, Snyder KV, Levy EI, Siddiqui AH, Meng H. AView: An Image-based Clinical Computational Tool for Intracranial Aneurysm Flow Visualization and Clinical Management. Annals of Biomedical Engineering, 44(4): 1085-96, 2016.
• Manini S, Antiga L, Botti L, Remuzzi A. pyNS, an open-source framework for 0D/1D hemodynamic modelling. Annals of Biomedical Engineering, 43(6): 1461-1473, 2015.
• De Momi E, Caborni C, Cardinale F, Casaceli G, Castana L, Cossu M, Mai R, Gozzo F, Francione S, Tassi L, Lo Russo G, Antiga L, Ferrigno G. Multi-trajectories automatic planner for StereoElectroEncephaloGraphy (SEEG). International Journal of Computer Assisted Radiology and Surgery. Int J Comput Assist Radiol Surg, 9(6): 1087-97, 2014.
• Botti L, Canneyt KV, Kaminsky R, Claessens T, Planken RN, Verdonck P, Remuzzi A, Antiga L. Numerical evaluation and experimental validation of pressure drops across a patient-specific model of vascular access for hemodialysis. Cardiovascular Engineering and Technology, 4(4): 485-499, 2013.
• Bacigaluppi S, Piccinelli M, Antiga L, Veneziani A, Passerini T, Rampini P, Zavanone M, Severi P, Tredici G, Zona G, Krings T, Boccardi E, Penco S, Fontanella M. Factors affecting formation and rupture of intracranial saccular aneurysms. Neurosurgical Reviews. Epub ahead of print, Dec 4, 2013. Cover.
• Caroli A, Perico N, Perna A, Antiga L, Brambilla P, Pisani A, Visciano B, Imbriaco M, Messa P, Cerutti R, Dugo M, Cancian L, Buongiorno E, De Pascalis A, Gaspari F, Carrara F, Rubis N, Prandini S, Remuzzi A, Remuzzi G, Ruggenenti P. Effect of longacting somatostatin on kidney and cyst growth in autosomal dominant polycystic kidney disease (ALADIN): a randomised, placebo-controlled, multicentre trial. The Lancet, 382(9903):1485-95, 2013.
• Remuzzi G, Benigni A, Finkelstein FO, Grunfeld JP, Joly D, Katz I, Liu ZH, Miyata T, Perico N, Rodriguez-Iturbe B, Antiga L, Schaefer F, Schieppati A, Schrier RQ, Tonelli M. Kidney failure: aims for the next 10 years and barriers to success. The Lancet, 382(9889):353-62, 2013.
• Van Canneyt K, Swillens A, Lovstakken L, Antiga L, Verdonck P, Segers P. The accuracy of ultrasound volume flow measurements in the complex flow setting of a forearm vascular access. J Vasc Access, 14(3):281-90, 2013.
• Caroli A, Manini S, Antiga L, Passera K, Ene-Iordache B, Rota S, Remuzzi G, Bode A, Leermakers J, Van de Vosse F, Vanholder R, Malovrh M, Tordoir J, Remuzzi A. Validation a patient-specific hemodynamic computational model for surgical planning of vascular access in hemodialysis patients. Kidney International, 84(6):1237-45, 2013.
• Piccinelli M, Vergara C, Antiga L, Forzenigo L, Biondetti P, Domanin M. Impact of hemodynamics on lumen boundary displacements in abdominal aortic aneurysms by means of dymamic computed tomography and computational fluid dynamics. Biomechanics and Modeling in Mechanobiology, 12(6):1263-76, 2013.
• De Momi E, Caborni C, Cardinale F, Castana L, Casaceli G, Cossu M, Antiga L and Ferrigno G. Automatic trajectory planner for StereoElectroEncephaloGraphy procedures: a retrospective study. IEEE Transactions on Biomedical Engineering, 60(4):986-93, 2013.
• Manini S, Passera K, Huberts W, Botti L, Antiga L and Remuzzi A. Computational model for simulation of vascular adaptation following vascular access surgery in hemodyalysis patients. Computer Methods in Biomechanics and Biomedical Engineering, Epub ahead of print, Jan 3 2013.
• Faggiano E, Antiga L, Puppini G, Quarteroni A, Luciani GB, Vergara C. Helical flows and asymmetry of blood jet in dilated ascending aorta with normally functioning bicuspid valve. Biomechanics and Modeling in Mechanobiology, 12(4):801-13, 2013.
• Passera K, Manini S, Antiga L, Remuzzi A. Patient-specific model of arterial circulation for surgical planning of vascular access. Journal of Vascular Access, 14(2):180-92, 2013.
• Schneiders JJ, Marquering HA, Antiga L, van den Berg R, Vanbavel E, Majoie CB. Intracranial Aneurysm Neck Size Overestimation with 3D Rotational Angiography: The Impact on Intra-Aneurysmal Hemodynamics Simulated with Computational Fluid Dynamics. AJNR, American Journal of Neuroradiology, 34(1):121-8, 2013.
• Piccinelli M, Hoi Y, Tong F, Veneziani A, Steinman DA, Antiga L. Automatic neck plane detection and 3D geometric characterization of aneurysmal sacs. Annals of Biomedical Engineering, 40(10):2188-211, 2012.
• Bijari PB, Antiga L, Gallo D, Wasserman BA, Steinman DA. Improved prediction of disturbed flow via hemodynamically-inspired geometric variables. Journal of Biomechanics, 45: 1632–1637, 2012.
• Cattaneo I, Condorelli L, Terrinoni AR, Antiga L, Sangalli F, Remuzzi A. Shear stress reverses dome formation in confluent renal tubular cells. Cell Physiol Biochem, 28(4):673-82, 2011.
• Passerini T, Sangalli LM, Vantini S, Piccinelli M, Bacigaluppi S, Antiga L, Boccardi E, Secchi, Veneziani A. An Integrated Statistical Investigation of Internal Carotid Arteries of Patients Affected by Cerebral Aneurysms. Cardiovascular Engineering and Technology, 3(1):26-40, 2012.
• Morbiducci U, Gallo D, Massai D, Ponzini R, Deriu MA, Antiga L, Redaelli A, Montevecchi FM. On the importance of blood rheology for bulk flow in hemodynamic models of the carotid bifurcation. Journal of Biomechanics, 44(13):2427-38, 2011.
• Vergara C, Viscardi F, Antiga L, Luciani GB. Influence of bicuspid valve geometry on ascending aortic fluid-dynamics: a parametric study. Artificial Organs, 36(4):368-78, 2012.
• Trachet B, Renard M, De Santis G, Staelens S, De Backer J, Antiga L, Loeys B, Segers P. An integrated framework to quantitatively link mouse-specific hamodynamics to aneurysm formation in angiotensin II – infused ApoE /mice. Annals of Biomedical Engineering, 39(9):2430-44, 2011.
• Caroli A, Antiga L, Conti S, Sonzogni A, Fasolini G, Ondei P, Perico N, Remuzzi G, Remuzzi A. Intermediate volume at CT imaging defines a fibrotic compartment that predicts GFR decline in ADPKD patients. American Journal of Pathology, 179(2):619-27, 2011.
• Bode A, Caroli A, Huberts W, Planken N, Antiga L, Bosboom M, Remuzzi A, Tordoir J. Clinical study protocol for the ARCH project – computational modeling for improvement of outcome after vascular access creation. Journal of Vascular Access, 12(4):369-76, 2011.
• Bijari PB, Antiga L, Wasserman BA, Steinman DA. Scan-rescan reproducibility of carotid bifurcation geometry from routine contrast-enhanced MR angiography. Journal of Magnetic Resonance Imaging. 33:482-489, 2011.
• Piccinelli M, Bacigaluppi S, Boccardi E, Ene-Iordache B, Remuzzi A, Veneziani A, Antiga L. Geometry of the ICA and recurrent patterns in location, orientation and rupture status of lateral aneurysms: an image-based computational study. Neurosurgery, 68(5):1270-85, 2011.
• Morbiducci U, Gallo D, Ponzini R, Massai D, Antiga L, Montevecchi FM, Redaelli A. Quantitative analysis of bulk flow in image-based hemodynamic models of the carotid bifurcation: the influence of outflow conditions as test case. Annals of Biomedical Engineering. 38(12):3688-705, 2010.
• Morbiducci U, Gallo D, Massai D, Consolo F, Ponzini R, Antiga L, Bignardi C, Deriu MA, Redaelli A. Outflow conditions for image-based hemodynamic models of the carotid bifurcation: implications for indicators of abnormal flow. Journal of Biomechanical Engineering. 132(9):091005-1-091005-11, 2010.
• Perico N, Antiga L, Caroli A, Ruggenenti P, Fasolini G, Cafaro M, Ondei P, Rubis N, Diadei O, Gherardi G, Prandini S, Panozo A, Bravo RF, Carminati S, De Leon FR, Gaspari F, Cortinovis M, Motterlini N, Ene-Iordache B, Remuzzi A and Remuzzi G. Sirolimus therapy to halt the progression of Autosomal Dominant Polycystic Kidney Disease: The SIRENA study. JASN, 21(6):1031-1040, 2010.
• Caroli A, Antiga L, Cafaro M, Fasolini G, Remuzzi A, Remuzzi G and Ruggenenti P. Reducing polycystic liver volume in ADPKD: effects of the extended release somatostatin analogue octreotide. CJASN, 5(5): 783-789, 2010.
• Viscardi F, Vergara C, Antiga L, Merelli S, Veneziani A, Puppini G, Faggian G, Mazzucco A and Luciani GB. Comparative finite element model analysis of ascending aortic flow in bicuspid and tricuspid aortic valve. Artificial Organs, 2010 Jul 4. Epub ahead of print.
• Botti L, Piccinelli M, Ene-Iordache B, Remuzzi A and Antiga L. An adaptive mesh refinement solver for large-scale simulation of biological flows. Communications in Numerical Methods in Engineering, 26(1): 86-100, 2010.
• Antiga L, and Steinman DA. Rethinking turbulence in blood. Biorheology, 46(2): 77-81, 2009.
• Ford MD, Hoi Y, Piccinelli M, Antiga L and Steinman DA. An objective approach to digital removal of saccular aneurysms: Technique and applications. The British Journal of Radiology, 82: S55-61, 2009.
• Piccinelli M, Veneziani A, Steinman DA, Remuzzi A and Antiga L. A framework for geometric analysis of vascular structures: application to cerebral aneurysms. IEEE Transactions on Medical Imaging, 28(8): 1141-55, 2009.
• Ene-Iordache B, Carminati S, Antiga L, Rubis N, Ruggenenti P, Remuzzi G, Remuzzi A. Developing regulatory-compliant electronic case report forms for clinical trials: the DEMAND trial. JAMIA, 16(3): 404-408, May-Jun 2009.
• Lee SW, Antiga L and Steinman DA. Correlations among indicators of disturbed flow at the normal carotid bifurcation. Journal of Biomechanical Engineering, 131(6), Jun 2009.
• Antiga L, Piccinelli M, Botti L, Ene-Iordache B, Remuzzi A and Steinman DA. An image-based modeling framework for patient-specific computational hemodynamics. Medical and Biological Engineering and Computing, 46: 1097-1112, Nov 2008.
• Antiga L, Wasserman B and Steinman DA. On the Overestimation of Early Wall Thickening at the Carotid Bulb by Black Blood MRI, with Implications for Coronary and Vulnerable Plaque Imaging. Magnetic Resonance in Medicine, 60(5): 1020-1028, Nov 2008.
• Lee SW, Antiga L, Spence JD and Steinman DA. Geometry of the carotid bifurcation predicts its exposure to disturbed flow. Stroke, 39(8): 2341-2347, Aug 2008. Featured on the front cover.
• Luciani D, Cavuto S, Antiga L, Miniati M, Monti S, Pistolesi M and Bertolini G. Bayes pulmonary embolism assisted diagnosis: a new expert system for clinical use. Emergency Medicine Journal (EMJ), 24:157-164, Mar 2007.
• Antiga L, Piccinelli M, Fasolini G, Ene-Iordache B, Ondei P, Ruggenenti P, Remuzzi G and Remuzzi A. Computed tomography evaluation of ADPKD progression: a progress report. Clinical Journal of the American Society of Nephrology (CJASN), 1(4): 754-760, Jul 2006.
• Moyle KR, Antiga L and Steinman DA. Inlet conditions for image-based CFD models: is it reasonable to assume fully-developed flow? Journal of Biomechanical Engineering, 128(3): 371-379, Jun 2006.
• Thomas JB, Antiga L, Che S, Milner JS, Hangan Steinman DA, Spence JD, Rutt BK and Steinman DA. Variation in the carotid bifurcation geometry of young vs. older adults: Implications for “geometric risk” of atherosclerosis. Stroke, 36(11): 2450-2456, Nov 2005.
• Ruggenenti P, Remuzzi A, Ondei P, Fasolini G, Antiga L, Ene-Iordache B, Remuzzi G and Epstein FH. Safety and efficacy of long-acting somatostatin treatment in autosomal dominant polycystic kidney disease. Kidney International, 68(1): 206-216, Jul 2005.
• Antiga L and Steinman DA. Robust and objective decomposition and mapping of bifurcating vessels. IEEE Transactions on Medical Imaging, 23(6): 704-713, June 2004.
• Antiga L, Ene-Iordache B and Remuzzi A. Computational geometry for patient-specific reconstruction and meshing of blood vessels from MR and CT angiography. IEEE Transactions on Medical Imaging, 22(5): 674-684, May 2003.
• Ene-Iordache B, Mosconi L, Antiga L, Bruno S, Anghileri A, Remuzzi G and Remuzzi A. Radial artery remodeling in response to shear stress increase within arteriovenous fistula for hemodialysis access. Endothelium, 10(2): 95-102, 2003.
• Remuzzi A, Ene-Iordache B, Mosconi L, Bruno S, Anghileri A, Antiga L and Remuzzi G. Radial artery wall shear stress evaluation in patients with arteriovenous fistula for hemodialysis access. Biorehology, 1-3: 423-430, 2003.
• Antiga L, Ene-Iordache B, Caverni L, Cornalba GP and Remuzzi A. Geometric reconstruction for computational mesh generation of arterial bifurcations from CT angiography. Computerized Medical Imaging and Graphics, 26(4): 227-235, June 2002.
• Antiga L, Ene-Iordache B, Remuzzi G and Remuzzi A. Automatic generation of glomerular capillary topological organization. Microvascular Research, 62: 346-354, June 2001.

Letters

• Steinman DA, Antiga A, Wasserman BA. Overestimation of cerebral aneurysm wall thickness by black blood MRI? Letter to the Editor. Journal of Magnetic Resonance Imaging 31:766, 2010.

Book chapters

• Antiga L, Peiró J and Steinman D. From image data to computational domain. Chapter 4 in Quarteroni A, Formaggia L and Veneziani A (eds), Cardiovascular Mathematics, Springer NY, 2008.

Open access papers

• Antiga L. Generalizing vesselness with respect to dimensionality and shape. The Insight Journal, 2007 July-December issue

Selected conf papers

• Antiga L. Pre-processing: from Image to CFD model. ISMRM CV Flow Workshop 2009, Sintra, Portugal, September 2009.
• Bijari PB, Antiga L, Steinman DA. Reliability of vascular geometry factors derived from clinical MRA. Proceeding of SPIE, Vol 7261, Orlando, FL, February 2009.
• Antiga L. Bridging the gap between shape and flow. Fifth International Bio-Fluid Symposium and Workshop, Caltech, Pasadena, CA, March 2008.

PhD thesis

• Antiga L. Patient-Specific Modeling of Geometry and Blood Flow in Large Arteries.